ESR1 and cancer: To validate the binding of the genes with these four antibodies, we examined 8 candidate genes that are involved in cancer progression, including Esr1 (Fig. 1l–n), Bcas3, and Bard1 (Supplementary Fig. 2m–p), as well as Crebbp, Myc, Rel, Gadd45g, and Shcbp1 (not shown).