To validate the binding of the genes with these four antibodies, we examined 8 candidate genes that are involved in cancer progression, including Esr1 (Fig. 1l–n), Bcas3, and Bard1 (Supplementary Fig. 2m–p), as well as Crebbp, Myc, Rel, Gadd45g, and Shcbp1 (not shown). This evidence concerns the gene REL and cancer.