SHCBP1 and breast cancer: Our analysis of these top candidates indicated that the expression levels of Shcbp1 were not only frequently upregulated in various cancers, including breast cancer [45], but were also identified in several signature gene lists of breast cancers, including 4 genes [46, 47], 5 genes [48], 8 genes [49], 9 genes [50], and 12 genes [51], for predicting survival, metastasis, and drug responses.