KEGG analysis of the 4652 (16.08%), 6105 (20.67%), and 4869 (16.86%) genes significantly modulated by gilteritinib indicated that gilteritinib primarily modulated signaling pathways associated with apoptosis, cell cycle, the mTOR pathway, AMPK pathway, p53 pathway, FOXO pathway, Hippo pathway, and Wnt pathway, which were essential for cancer cell proliferation and metastasis. Here, TP53 is linked to cancer.