In recent years, various food proteins, traditional Chinese medicine components, and cell extracts have been found to enhance antioxidant, ADH, and ALDH2 activity, reducing liver steatosis, cell apoptosis, and alcohol-induced liver toxicity.79, 80, 81, 82Given the important role of ALDH2 and the large population of mutation carriers, the targeting of ALDH2 is a promising therapeutic strategy for ALD. The gene discussed is ALDH2; the disease is fatty liver disease.