Moreover, protein analysis revealed decreased CAT, ADH1A, ADH1B, and ADH4 and increased ALDH2 in both groups, while ALDH1A1 and ALDH1B1 reduction occurred only in the >5% fat group.92Moreover, in a population of mainly non-Hispanic white patients, compared withADH1B*1,ADH1B*2was associated with a lower incidence of MASH and fibrosis.93 This evidence concerns the gene ADH4 and metabolic dysfunction-associated steatohepatitis.