A recent meta-analysis of data from genome-wide association studies indicated thatALDH2*1/*1is a susceptibility variant for T2DM in East Asian male populations.107Moreover, compared toALDH2*2carriers,ALDH2*1/*1carriers increase alcohol intake, reduce fasting blood glucose clearance, and promote hepatic insulin resistance, elevating fasting glucose levels and T2DM's susceptibility.108. This evidence concerns the gene ALDH2 and type 2 diabetes mellitus.