IGHE and asthma: In a Scottish cohort of moderate to severe asthma patients, there was considerable overlap of T2 biomarkers according to eosinophils ≥ 300/μL, FeNO ≥ 25 ppb, and total IgE ≥ 100 kU/L, where 24.7% of patients were classified as being triple T2 high and 18.5% triple T2 low [33].