These inhibitory effects were more prominent in treatment with ac-LA than with lupeol, and inhibitory effects of ac-LA were comparable to those of docetaxel.48 Similar inhibitory effects on Akt and mTOR signaling were also observed in treatment of androgen-independent prostate cancer cells treated with α-acetoxy-tirucallic acid αATA (8,24).49 This treatment was associated with increased apoptosis both in vitro and in vivo xenografts of the cancer cells, without significant toxicity to normal cells.49 Boswellic acid can also increase antioxidant response. The gene discussed is AKT1; the disease is prostate carcinoma.