Treatment of docetaxel-resistant prostate cancer cells (PC3/Doc) with AKBA isolated from Boswellia showed dose-dependent inhibition of proliferation and induction of apoptosis in these cells.47 These inhibitory effects on cancer cells were associated with decreased levels of Akt and STAT3 and inhibition of their signaling pathway. The gene discussed is AKT1; the disease is Familial prostate cancer.