One cohort study of CAA (n = 67), AD (n = 76), mild cognitive impairment (MCI) related to AD (n = 75), MCI unrelated to AD (n = 76), and controls (n = 78) noted the following patterns of CSF biomarker profiles: (1) reductions in CSF Aβ40 in CAA compared to controls, AD and MCI‐AD, and (2) elevations in t‐tau and p‐tau in CAA compared to MCI‐non‐AD and controls, but lower than AD and MCI‐AD.45 The gene discussed is MAPT; the disease is Cognitive impairment.