Current scoring systems designed to evaluate the severity of liver failure encompass a range of models such as Child-Turcotte-Pugh (CTP), APASL ACLF Research Consortium (AARC), Model for End-stage Liver Disease (MELD), Model to Estimate Survival in Overt Hepatic Failure (MESO), Age-Bilirubin-INR-Creatinine (ABIC), Maddrey Discriminant Function (MDF), Albumin-Bilirubin (ALBI), Acute Physiology and Chronic Health Evaluation (APACHE), Chronic Liver Failure Consortium (CLIF-C), among others [2–6]. The gene discussed is ALB; the disease is liver failure.