They also attenuated levels of adhesion molecules (Icam-1, Vcam-1), and monocyte chemoattractant protein (Mcp1) which led to the restoration of the mucosal layer and improvements in symptoms [81].Ethanolic extract was utilized to treat and prevent early stages of atopic dermatitis by downregulation of the NF-kB pathway and inhibition of IgE release from B cells and mast cell activation resulting in symptomatic relief [82]. Here, NFKB1 is linked to atopic eczema.