ITGA9 and Familial prostate cancer: ITGA9 has been reported to be upregulated in various cancers, including glioblastoma, melanoma, hepatocellular carcinoma, and prostate cancer, and is closely associated with angiogenesis and lymph-angiogenesis [30], and cell proliferation and migration [31], suggesting a potential role of ITGA9 in tumor development [32].