ROC curve analysis was conducted to compare tsRNA-49:73-Glu-CTC with commonly utilized clinical tumor markers (CEA, NSE, CYFRA), revealing that tsRNA-49:73-Glu-CTC achieved an AUC of 0.785, with a sensitivity of 68.8% and a specificity of 84.2%. This evidence concerns the gene CEACAM5 and neoplasm.