Processes relating to metabolism and hormonal regulation (Insulin secretion, GnRH signaling pathway, Cortisol synthesis and secretion, Endocrine regulated calcium reabsorption, Oxytocin signaling pathway, PAC1 receptor pathway) and ECM and cell adhesion (ECM-receptor interaction, NCAM1 interactions, PECAM1 interactions, Cell to cell adhesion signaling, EGFR interaction with phospholipase C-gamma, Heparan sulfate proteoglycan biosynthetic process) are also among the top 15 significantly enriched processes (Table S2), which are linked to NASH [35–37]. This evidence concerns the gene PECAM1 and metabolic dysfunction-associated steatohepatitis.