Functional enrichment of DMEGs and protein-protein interaction network analyses aligned with our previous protein and gene expression and physiological findings [15,16], showing an enrichment in hepatic fibrosis, PI3K-Akt and Foxo signalling, oxidative phosphorylation, insulin signalling/secretion, NAFLD and T2DM pathways. This evidence concerns the gene INS and metabolic dysfunction-associated steatotic liver disease.