Hence, 125 articles remained for full-text screening, 114 of which were excluded for the following reasons: not evaluating TLR4-related outcomes (n = 24), evaluating outcomes in populations other than people with schizophrenia (n = 5), being non-original articles (n = 64), animal studies (n = 9), in vitro studies (n = 5), post-mortem studies (n = 4), and non-English studies (n = 2). The gene discussed is TLR4; the disease is schizophrenia.