CEACAM5 and gastric cancer: In univariate analysis, factors associated with mortality in GC patients were age greater than 65 years (HR: 1.76; 95% CI: 1.17-2.65; p = 0.006), female gender (HR: 2.38; 95% CI: 1.50-3.79; p < 0.001), stage IV disease (HR: 2.29; 95% CI: 1.02-5.14; p = 0.044), high CEA levels (≥ 5 ng/mL) (HR: 1.53; 95% CI: 1.01-2.33; p = 0.047), and neoadjuvant chemotherapy (HR: 0.57; 95% CI: 0.34-0.98; p = 0.042) (Table 3).