ACA, anti-centromere antibodies; AIH/PBC OS, autoimmune hepatitis/primary biliary overlap syndrome; AMA, anti-mitochondrial antibodies; APRI, AST-to-platelet ratio index; ELF score, enhanced liver fibrosis score; HK1, hexokinase-1; KLHL12, kelch-like 12 protein; LSM, liver stiffness measurement; MRE, magnetic resonance elastography; ULN, upper limit of normal. This evidence concerns the gene KLHL12 and autoimmune hepatitis.