In univariate logistic regression analysis with left ventricular ejection fraction, end-diastolic internal diameter, end-systolic internal diameter, PTFV1 < −0.03 mm s, gal-3, and TGF-β1 as independent variables, gal-3, and TGF-β1 were the risk factors for poor collateral circulation for stroke due to AF, and then included in the multifactorial logistic regression analysis, and neither was an independent risk factor. The gene discussed is LGALS3; the disease is Stroke.