TNFRSF13B and pulmonary arterial hypertension: These were DCLRE1C; NM_001033855.3 c.207_209del (p.Leu70del) – rs753202682- homozygous and TNF Receptor Superfamily Member 13B (TNFRSF13B); NM_012452.3 c.260T >A (p.Ile87Asn)–rs72553877 heterozygous variant in genes related to the immune system; and PAH: NM_000277.3 c.688G >A (p.Val230Ile)–rs62516152 homozygous variant in genes related to amino acid metabolism.