Interestingly, the breast cancer cell-derived exosomes Exo-MCF-7 and Exo-MDA-MB-231 induced increased expression of α-SMA and FAP in fibroblasts, and the potency of Exo-MDA-MB-231 was greater than that of Exo-MCF-7 (Figure 1D). The gene discussed is FAP; the disease is breast carcinoma.