SPINK1 and hypertriglyceridemia: Numerous factors contribute to the condition, such as autoimmune pancreatitis, hypertriglyceridemia, and lifestyle factors, as shown in Figure 1; post-endoscopic retrograde cholangiopancreatography (ERCP), medications, genetic risk (mutations in the CFTR (cystic fibrosis trans-membrane conductance regulator protein) and SPINK1 (serine protease inhibitor Kazal type 1) genes that cause gain of function), and pancreatic duct injury are also among the causes [21].