ACE and COVID-19: The risk of COVID-19 disease was found to elevate in the presence of ACE1 rs4646994ins/ins + PPARGC1A rs8192678TC, ACE1 rs4646994ins/del + PPARGC1A rs8192678TC, and ACE1 rs4646994del/del+ PPARGC1A rs8192678TC genotypes, but no statistically significant differences were found when ACE1 rs4646994-ins/ins and ACTN3 rs1815739 CC combined genotypes compared to other genotypes.