Deng et al. (2025) also implicated OSGIN-1 in the ferroptosis of ovarian cancer cells; while ovarian cancer cells treated with erastin, a molecule known to induce ferroptosis, demonstrated decreased levels of ROS, malondialdehyde (MDA), and iron, knockdown of OSGIN-1 restored these ferroptosis biomarkers to near-baseline levels [57]. This evidence concerns the gene OSGIN1 and ovarian cancer.