While some studies have partially elucidated Osgin’s mechanistic role in pathways like p-AMPKαT172 autophagy [91] or protein–protein interactions with TUBB3 [55], a large share of research related to Osgin1 or Osgin2 are wide-reaching cancer expression analyses, reporting differential expression across a wide variety of genes with varied and potentially unrelated physiological function. The gene discussed is OSGIN1; the disease is cancer.