It was reported that exosomes reduced lipid peroxidation, slowed lung damage, and suppressed inflammatory cytokines by inducing antioxidant enzymes in mice, in which sepsis induced acute lung injury andreppressed NADPH oxidase 4 (NOX4), which is the target of miRNA 182-5p and involved in mitochondrial functions in LPS-stimulated MLE-12 lung epithelial cells [145]. The gene discussed is NOX4; the disease is Sepsis.