GRM7 variants may predict the risk of schizophrenia and antipsychotic effects of common drugs: rs1516569 in GRM7, a significant risk factor (OR = 0.95, p < 3.47 × 10−4), and rs9883258 in GRM7 (OR = 0.84, p = 2.18 × 10−3) are potential biomarkers for therapeutic responses of seven commonly used antipsychotic drugs (aripiprazole, haloperidol, olanzapine, perphenazine, quetiapine, risperidone, and ziprasidone) in the Chinese Han population. Here, GRM7 is linked to schizophrenia.