A recent review of the early results of the Collaborative Study on the Genetics of Alcoholism (COGA) candidate gene studies provided information on the tachykinin receptor, bitter taste receptor genes, and ADH1B, GABRA2, CRHR1, CHRM2, GRM8, DRD2/ANKK1, HTT, OPRK1 and PDYN, ACN9 NFKB1, GABRR1, GABRR2, CRHR1, SGIP1, CHRNA5, NPY and SNCA see [105]. This evidence concerns the gene GRM8 and alcohol dependence.