Although according to the Schizophrenia Working Group, GRM7 is not reflected among the “credible causal schizophrenia SNPs, coding variants, and eQTLs” [129], following and expanding upon the research on schizophrenia in the Chinese Han population, the interactions between two Group III mGluR genes, GRM7 and GRM8, were studied in a population with SCZ and major depressive disorders (MDD) in samples of 1235 SCZ patients, 1045 MDD patients, and 1235 normal controls. This evidence concerns the gene GRM8 and schizophrenia.