Traditional preparations, such as the Qing-re-huo-xue formula combining Scutellaria baicalensis and Radix paeoniae rubra, show synergistic effects by activating the p53 and GSK-3β/Nrf2 pathways, inducing ferroptosis and apoptosis in NSCLC [151]. Here, GSK3B is linked to non-small cell lung carcinoma.