As listed in Table 1, these analyses reveal consistent patterns of PHI-1 dysregulation across multiple cancer types, such as bladder urothelial carcinoma (BLCA), endometrial carcinoma (UCEC), prostate cancer (PRAD), glioblastoma multiforme (GBM), and triple-negative breast cancer (TNBC), indicating its broad relevance in cancer biology. Here, PPP1R14B is linked to Familial prostate cancer.