STAT3 and colonic neoplasm: In concordance with this, it has been shown that early treatment using molecules excreted/secreted by Taenia crassiceps (TcES) in a colitis-associated colon cancer (CAC) mouse model leads to reduced pro-inflammatory and proliferative signaling pathways related to cancer establishment and progression, such as STAT3/NFκB, indicating that these molecules may be an excellent early adjuvant therapy in experimental CRC treatment [76].