Interestingly, these findings are in agreement with what Moreno et al. described in patients with type 2 diabetes, where high serum adiponectin levels were inversely associated with eGFR even after controlling for several confounding factors such as sex, smoking habits, body mass index, waist circumference, diabetes duration, glycated hemoglobin (HbA1c), albumin creatinine ratio, and anti-hyperglycemic, anti-hypertensive, and anti-dyslipidemic treatments [48]. The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.