IL10 and fetal growth restriction: In a study with pregnant rats, it was shown that inducing IUGR during the final trimester (days 14 to 20) is possible, and the effects can be attenuated by administering IL-10, indicating that IUGR relies, to some extent, on how placental cytokines, such as IL-10, interact and impact placental growth, development, or function [57,58].