In discrimination between the POAG and cataract groups (Figure 4C, Supplementary Table S3), the AUCs of ETNK1 and VMAC were calculated to be 0.820 (95%CI: 0.733–0.907) and 0.889 (95%CI: 0.818–0.959), respectively. This evidence concerns the gene ETNK1 and open-angle glaucoma.