TNNT2 and Patent ductus arteriosus: EL-Khuffash et al. demonstrated that cTnT may be a valuable marker of ductal significance and treatment response due to its correlation with echocardiographic markers (ductal diameter, left atrial-to-aortic diameter ratio, and descending aortic end-diastolic velocity) of PDA [(AUC of 0.78 (95% CI 0.66 to 0.90; p < 0.001))].