GH1 and metabolic syndrome: In contrast, Sjöström et al. reported increased hemoglobin A1c (HbA1c) and decreased LDL cholesterol, with a concomitant CPP increase in patients treated with GH [54], whereas an association was revealed between CPP, metabolic syndrome, BMI, plasma glucose levels, insulin resistance, TG, and HDL cholesterol in the American population [56].