CASP8 and neoplasm: Immunohistochemical results suggested that in tumor tissues, CASP8 and SAMSN1 showed high staining, TXNIP showed medium staining, while KLF6 and XCL1 showed negative staining; in normal tissues, KLF6 showed medium staining, CASP8 and SAMSN1 showed low staining, while TXNIP showed negative staining (Figure 4H).