Immunohistochemical staining recently revealed elevated p70S6K1 phosphorylation in invasive ductal carcinoma (IDC) tissues extracted from postmenopausal women with T2DM, in contrast to their non-DM counterparts [14], suggesting p70S6K1 overphosphorylation may serve as a therapeutic target and potential biomarker for invasive BC in T2DM patients. Here, RPS6KB1 is linked to invasive ductal breast carcinoma.