AIP and obesity due to melanocortin 4 receptor deficiency: Bivariate analysis for comorbidities and clinical conditions in the population with morbid MetS vs. non-MetS showed OR 3.0 for hyperuricaemia; ORs between 5.5 and 9.6 for obesity, high-WtHR, hypercholesterolaemia, high-AIP, high-LAP, high-TyG index, high-FLI, AF, erectile dysfunction, albuminuria, low eGFR, and CKD; and highlighted HF and CUN-BAE EA, with ORs 11.0 and 17.0, respectively (Figure 3b, Table S4, Supplementary Materials).