Patients with diabetes that showed peripheral neuropathy had elevated levels of leptin, sE-selectin, soluble intercellular adhesion molecule (sICAM-1), soluble vascular cell adhesion molecule (sVCAM-1), CRP, fibrinogen, platelet-derived growth factor (PDGF) AB/AA, and regulated upon activation normal T cell expressed and secreted (RANTES) [71]. Here, CRP is linked to diabetes mellitus.