Another study revealed that the hypomethylation of genes such as CLEC14A (cell adhesion), MYO15B (actin and ATP binding), LTBR (programmed cell death), TMEM132D and TTC34 (transmembrane transporters and regulators) was the best predictive epigenetic marker for BC susceptibility to NACT [26]. The gene discussed is LTBR; the disease is breast cancer.