HCRT and Insulin resistance: An imbalance in the OX system can therefore lead to a variety of metabolic disorders such as dyslipidemia, as shown by studies that linked OX gene expression with hypertriglyceridemia [50] and insulin resistance [51], and could be important for the development of type 2 diabetes [46], for which, as for insulin resistance, there is an increased risk following COVID-19 infection [52].