84 outpts 18–50 years with DSM-IV-TR SCZ ≥ 2-year DoI, clinically stable × 4 wks, treated with same RISP dose × 8 wks. Exclusion criteria: ECT in last 3 months, abnormal bleeding, PANSS Depression item ≥ 4; HAM-D score ≥ 14, IQ < 70. Cilostazol+ RISP (42; ♂ 37, ♀ 5, x- age 37.40 ± 7.80 years), RISP +plac (42; ♂ 37, ♀ 5, x- age 36.19 ± 7.18 years). The gene discussed is UQCRFS1; the disease is major depressive disorder.