This analysis revealed 13 differentially expressed genes, with 8 genes (CCL19, CCL2, CXCL13, IL1R2, MS4A1, TNFRSF17, IRF4, and CCL8) significantly downregulated and 5 genes (CXCL8, CSF2, CXCL11, CCL3, and CCL20) upregulated in CRC tissues. Here, IRF4 is linked to colorectal carcinoma.