CRP and infection: Kusumoto et al. [25] focused on the utility of routine blood tests and specific indices, like the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score and the combined C-reactive protein (CRP) + Neutrophil-to-Lymphocyte Ratio (NLR), in differentiating between severe infection groups, such as deep neck abscess and necrotizing soft tissue infection (NSTI).