We comprehensively analyzed eleven scRNA datasets with 8257 normal podocytes, three scRNA CKD datasets with 2946 podocytes, three AKI datasets with 1471 podocytes, and one type 2 diabetes mellitus dataset with 390 podocytes and detected PLA2R1 as being in the top two or three upregulated genes in the comparison settings of CKD to normal, AKI to normal, and DN to normal (Table 1). This evidence concerns the gene PLA2R1 and chronic kidney disease.