The search terms included ‘interleukin-10’ or ‘IL-10’, ‘Pegilodecakin’ with ‘cancer’, ‘tumour’, ‘neoplasia’, ‘immunotherapy’, ‘biological therapy’, ‘cell proliferation’, ‘apoptosis’, ‘metastasis’, ‘epithelial–mesenchymal transition (EMT)’, ‘tumour microenvironment (TME)’, ‘tumor-associated macrophages (TAMs)’, ‘tumor infiltrated immune cells’, and ‘cancer immunology’. This evidence concerns the gene IL10 and cancer.