A significant association between BC and 12 gene variants was identified in the following genes: rs3856806 (PPARG), rs3917542 (PON1), rs3750804 and rs3750805 (TCF7L2), rs12792229 (MMP8), rs1121980 and rs3751812 (FTO), rs12946618 (RPTOR), rs2833483 (SCAF4), rs1800955 (SCT-DEAF1-DRD4), rs5218 (KCNJ11-ABCC8), and rs11652805 (AMZ2P1-GNA13) (Table 4). The gene discussed is TCF7L2; the disease is breast cancer.