DDIT3 and neoplasm: This described effect occurred via activation of the C/EBP homologous protein (CHOP)/tribbles-related protein 3 (TRB3)/caspase 3 axis and the upregulation of calreticulin, which triggered PM cell phagocytosis by dendritic cells and increased the abundance of anti-tumor CD8+/CD107+ cytotoxic lymphocytes.