CYP3A4 and Obesity: However, the educational film’s impact on prescribing practices in this population was suboptimal, increasing from 40.5% to 56.1% in case 7 (obesity, unvaccinated, and no CYP3A-metabolized drugs) and from 37.0% to 55.5% in case 8 (obesity, unvaccinated, and CYP3A-metabolized drugs).