Subsequent in vitro experiments demonstrated that the expression of E-cadherin in BLCA cells with OBSCN expression deficiency was significantly reduced, while the expression of N-cadherin, Vimentin, Snail, and Slug were significantly increased, indicating that OBSCN expression deficiency enhanced the ability of EMT in BLCA cells (Fig. 3H). Here, CDH2 is linked to bladder transitional cell carcinoma.