Seven of the suspected IE dogs were excluded based on our predefined exclusion criteria, including elevated urinary bile acids: creatinine ratio (n = 2); elevated CRP and leucocytosis (n = 1), hypoalbuminemia and hyperglobulinemia with increased alfa-2 serum protein fraction (n = 1), suspected protein-losing enteropathy (n = 1), only a single episode of seizure presented along the study period (n = 1) or suspected paroxysmal dyskinesia (n = 1). This evidence concerns the gene CRP and Hypoalbuminemia.