S1), which implied increased neutrophil infiltration in the cancerous tissues of breast cancer patients. Furthermore, after immunofluorescent labeling of NETs markers in the tissues, MPO and CitH3 experienced an elevated expression in cancerous tissues in comparison with normal tissues, which suggested that NETs saw an increased formation in the tissues of breast cancer patients (Fig. 1D; Tab. S1). The gene discussed is MPO; the disease is breast cancer.