TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: To investigate whether the elevated TFE3-driven OxPhos in the 4 tRCC cell lines was also seen in human patient samples, we integrated clinical and RNA-seq data of 37 TFE3-tRCC primary samples and 2 metastasis samples (from the same patient, therefore 38 patients and 39 samples) from a cohort of patients from American and French institutes and TCGA whose clinical and pathological features are summarized in Fig. EV4A,B and Dataset EV5.