Comparison with the tRCC clusters showed that although ccRCC.epi had a comparable OxPhos score to tRCC clusters 1 and 2 and to NAT, all tRCC clusters showed significantly higher OxPhos score than ccRCC.int and ccRCC.mes (Fig. 4D and Dataset EV6). The gene discussed is BRD2; the disease is nonpapillary renal cell carcinoma.