GATA2 and acute myeloid leukemia: In 2011, a 50-year-old woman was diagnosed with acute myeloid leukemia (AML) with monosomy 7, and was reported to have GATA2 deficiency after molecular profiling on blood identified two germline GATA2 variants (p.Thr358Lys and p.Leu359Val) in the second zinc finger which were found to reside in cis.