IDH1 and glioblastoma: In particular, we considered datasets from two IDH wild-type donors of scRNA-Seq (GSE129671; (Ding et al, 2019; Data ref: Ding et al, 2019) (Fig. 1D,E), bulk RNAseq data of IDH wild-type samples from The Cancer Genome Atlas study of GBM (Data ref: TCGA-GBM; phs000178) (Fig. 1F), proteomic data of IDH wild-type GBM (PDC000204; (Wang et al, 2021; Data ref: Wang et al, 2021) (Fig. 1G) and scRNA-seq data of healthy adult brain tissue (GSE67835; (Darmanis et al, 2015; Data ref: Darmanis et al, 2015) as control (Fig. 1H).